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Researchers have made great progress in the mechanism of mycotoxins biosynthesis, pathogenicity, and the construction of detection methods. This collection holds fundamental and applied research on pathogenic fungi and mycotoxins in China, which directly or indirectly affect the health of plants, animals, and humans. Some papers mainly study the mechanism of mycotoxin biosynthesis, including the crucial genes, environmental factors, and regulation mechanisms, which is beneficial to advancing our knowledge of this area. Some papers focus on the toxicity of mycotoxins, which is helpful to the detoxification of mycotoxins and the reduction of the hazardous effect of mycotoxins. Special attention is given to the leading detection methods, especially on-site rapid detection. These effective and feasible methods are important for discovering and controlling the risk of mycotoxins.

Mycotoxins. --- Fungal toxins --- Fungal metabolites --- Microbial toxins --- Mycotoxicoses --- Toxigenic fungi

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Mycotoxins --- Toxigenic fungi --- Food contamination --- Feeds --- Food --- Mycotoxicoses --- Contamination --- Microbiology

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Mycotoxins --- Mycotoxicoses --- Mycotoxins. --- Mycotoxicoses. --- Fungal toxins --- Fungi --- Toxigenic fungi --- Fungal Toxins --- Toxins, Fungal --- Toxicology --- Mycotoxines --- Mycoses --- Poisoning --- Fungal metabolites --- Microbial toxins --- Mushroom Poisoning --- Mycotoxin --- Mycotoxines.

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This book provides information on the incidence of fungi and mycotoxins in some African countries, the health implications and possible intervention control strategies for mycotoxins in developing countries and in Africa in particular. It will therefore be of interest to students, educators, researchers and policy makers in the fields of medicine, agriculture, food science and technology, trade and economics. Food regulatory officers also have quite a lot to learn from the book. Although a lot of the generated data in the area of mycotoxicology are available to the developed world, information on the subject area from Africa is scanty and not usually available in a comprehensive form. This book attempts to address the gap. Being an open access book, it will be of great benefit to scientists in developing countries who have limited access to information due to lack of funds to pay or subscribe for high quality journals and data from commercial publishing and database companies.

Mycotoxins. --- Food --- Safety measures. --- Fungal toxins --- Fungal metabolites --- Microbial toxins --- Mycotoxicoses --- Toxigenic fungi --- Medical toxicology

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Mycotoxins are secondary metabolites produced by molds. Although the primary role of these toxins is thought to be related to the colonisation of the environment by the fungi--mycotoxins are able to kill other micro-organisms (antimicrobial effect) and/or plant cells (mycotoxin-producing fungi being necrophagic)--the exposure of animals and humans to mycotoxins through the consumption of mycotoxin-contaminated food and feeds leads to diseases and death. Among the different mycotoxins described (more than 350 mycotoxins have been identified), deoxynivalenol (DON or vomitoxin) produced by Fusarium species has attracted the most attention due to its prevalence and toxicity. DON is part of a family of mycotoxins called trichothecenes that are small sesquiterpenoids with an epoxide group at positions 12-13 allowing their binding to ribosomes causing the so-called ribosome stress response, characterized by the activation of various protein kinases that lead to alterations in gene expression and cellular toxicity in animals, humans and plants. Here, we compiled very recent findings regarding DON and its derivatives: i. their prevalence in human food; ii. the estimation of the exposure of humans to them using biological markers; iii. their roles during plant-fungi interaction; iv. the alteration caused by them in animals and humans, particularly at low doses that are close to those observed in farm animals and human consumers; v. possible strategies to decrease their presence in food and feeds. Overall, this book will give the reader a clear and global view on this important mycotoxin produced by Fusarium species which is responsible for huge economic loss and health issues. Dr. Marc Maresca Guest Editor.

Mycotoxins --- Mycotoxins. --- Fungal toxins --- Fungal metabolites --- Microbial toxins --- Mycotoxicoses --- Toxigenic fungi